SPINA CARB: A SIMPLE MATHEMATICAL MODEL SUPPORTING FAST IN-VIVO ESTIMATION OF INSULIN SENSITIVITY AND BETA CELL FUNCTION

SPINA Carb: a simple mathematical model supporting fast in-vivo estimation of insulin sensitivity and beta cell function

Abstract Modelling insulin-glucose homeostasis may provide novel functional insights.In particular, simple models are clinically useful if they yield diagnostic methods.Examples include the homeostasis model assessment (HOMA) and the quantitative insulin sensitivity check index (QUICKI).However, limitations of these approaches have been criticised.

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Noninvasive oxygenation strategies in adult patients with acute respiratory failure: a protocol for a systematic review and network meta-analysis

Abstract Background Acute hypoxemic respiratory failure is one of the leading causes of intensive care rohrventilator industrie unit admission and is associated with high mortality.Noninvasive oxygenation strategies such as high-flow nasal cannula, standard oxygen therapy, and noninvasive ventilation (delivered by either face mask or helmet interfa

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The Role of Immunohistochemical Analysis as a Tool for the Diagnosis, Prognostic Evaluation and Treatment of Prostate Cancer: A Systematic Review of the Literature

Background: Prostate cancer (PCa) is a heterogeneous disease that lends itself toward numerous therapeutic options depending on its risk stratification.One of the greatest challenges in PCa urologic practice is to select patients who should be referred for biopsy and, for those patients who are diagnosed with cancer, to differentiate between patien

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